Journal: Psychiatry research
Article Title: Acute Change in Anterior Cingulate Cortex GABA, but not Glutamine/Glutamate, Mediates Antidepressant Response to Citalopram
doi: 10.1016/j.pscychresns.2017.08.009
Figure Lengend Snippet: Sagittal MRI showing placement of magnetic resonance spectroscopy (MRS) voxel in the pregenual anterior cingulate cortex and sample 3 Tesla proton MRS spectra from the pregenual anterior cingulate cortex at baseline (scan 1), day 3 (scan 2), day 7 (scan 3), and day 42 (scan 4) using J-PRESS (extracted from J = 0.0Hz) and MEGAPRESS sequences. Spectra are displayed with LCModel fit and residual. Cho, choline; Cr, creatine; GABA, gamma-amino-butyric acid; Glu, glutamate; mI, myo-inositol; NAA, N-acetylaspartate.
Article Snippet: Every J -resolved spectral extraction within a bandwidth of 67Hz was fit with the spectral-fitting package LCModel ( Provencher, 1993 ) and its theoretically-correct template.
Techniques: Spectroscopy